PRECONCEPTION GENETIC TESTING
Preconception testing is performed before conceiving. It enables the analysis of the genetic compatibility of partners and helps to adjust the treatment specifically for the couple.
This panel was developed at Repromeda clinic, tailored especially for patients who come with fertility issues, as well as for those trying to conceive naturally. This test completely replaced methods used in preconception genetic diagnosis previously.
This genetic test is designed to detect hidden gene mutations in couples. The goal of such examination is to reduce the risk of birth of a child affected by the severe monogenic disease. Currently, we perform screening of 110 genes linked to clinically most relevant monogenic diseases.
PANDA Exom is a genetic test that detects mutations in all known genes responsible for monogenic diseases (clinical exom). It is the examination of the widest extent that could possibly be offered to a couple for testing hidden (recessive) mutations.
Each human cell normally contains 46 chromosomes. But human chromosomes also differ. Twenty-two of these are called autosomes, one from each mother’s and father’s pairs. There are also two sex chromosomes called gonosomes, which are responsible for sex determination.
PREIMPLANTATION GENETIC DIAGNOSIS
Preimplantation genetic testing is a method that allows the diagnosis and selection of a suitable embryo prior to its transfer into the uterus.
PGT-M: PREIMPLANTATION GENETIC TESTING FOR MONOGENIC DISORDERS
Currently we use the Karyomapping method. The examination is thus suitable both for all monogenic disorders and for hereditary cancer syndromes as well.
PGT-A: PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDIES
Preimplantation genetic testing for aneuploidies is performed during IVF treatment. It increases treatment success by selecting the most perspective embryo for transfer.
PGT-SR: PREIMPLANTATION GENETIC TESTING FOR STRUCTURAL CHROMOSOMAL REARRANGEMENTS
PGT of structural chromosomal rearrangements is suitable for couples where one or both partners are carriers of a balanced translocation or other structural chromosomal abnormality.
Liquid handling workstation Sciclone G3 NGS
To prepare sequencing libraries for preconception diagnostics and PGT-A, we use a modern automatic liquid handling workstation Sciclone G3 NGS, which not only significantly speeds up and simplifies the sample preparation process, but also helps us to achieve maximum accuracy and reliability of the whole process.
We are both an IVF centre and a medical genetics clinic. Thanks to this, we know the needs of our customers well.
We have set up our approach and services in such a way so that we can precisely, while sensitively provide genetic examinations for several other clinics. The cooperation is set individually, but always without compromising the quality.